Best Presentation Award Winner 2016

2016

Category-1: Hematopoiesis and Immune Environment

3-E-W30-2-O/P
Local function of the IL-15 niche in thymus
Guangwei Cui (Kyoto University)
3-E-W30-10-O/P
An organ-wide transcriptome of collagen-producing cells identifies the core signature of steady-state murine fibroblasts
Shigeyuki Shichino (The University of Tokyo, AMED)


Category-2: B cells

2-B-W16-10-O/P
Dynamics of IRF4-dependent gene activation and repression during plasma cell differentiation
Kyoko Ochiai (Tohoku University School of Medicine, AMED-CREST)
2-B-W16-14-O/P
LRRK1 controls B-cell responses by regulating CARMA1-dependent NF-κB activation
Keiko Morimoto (Osaka University)


Category-3: T cells

1-G-W13-3-O/P
Timing and duration of MHC-I positive selection signals in the thymus reveal a novel compensatory signaling mechanism that prevents lineage fate errors
Motoko Kimura (Chiba University)
1-G-W14-11-O/P
Membrane lipid binding by SH2 domains of Lck and Zap70 regulates T cell receptor activation
You-Me Kim (Pohang University of Science and Technology)


Category-4: Helper T cells

3-G-W34-3-O/P
Gai-coupled non-canonical Hedgehog signaling in human Naive CD4 T lymphocytes.
Olga Elisseeva (Okinawa Institute of Science and Technology Graduate University)
3-G-W34-5-O/P
The microRNA-183/96/182 cluster promotes T helper 17 cell pathogenicity by negatively regulating transcription factor Foxo1 expression
Kenji Ichiyama (Osaka University, Children's National Medical Center)


Category-5: Regulatory T cells

3-G-W35-5-O/P
Soluble form of CTLA-4 produced by regulatory T cells facilitates M2 macrophage differentiation in auto-inflammatory condition.r> Motonao Osaki (Kyoto University, Osaka University)
3-G-W35-8-O/P
Immunological significance of dual secretion of TGF-β3 and IL-10 from regulatory T cells
Toshihiko Komai (The University of Tokyo)


Category-6: Innate lymphocytes

1-C-W5-3-O/P
Identification of an alternative developmental pathway of Va14+ NKT cells from double-negative thymocytes
Nyambayar Dashtsoodol (RIKEN-IMS, Mongolian National University)
1-C-W6-7-O/P
IFN regulatory factor 2 controls ILC development by promoting PLZF+ILC progenitor generation.
Yohei Okubo (Shinshu University)


Category-7: Dendritic cells and macrophages

1-B-W3-1-O/P
Single-cell RNA-seq reveals a novel dendritic cell-primed early progenitor population
Daisuke Kurotaki (Yokohama City University)
1-B-W4-4-O/P
MafB is the primary regulator of complement component C1q
Michito Hamada (University of Tsukuba)


Category-10: Mast cells & granulocytes

2-E-W19-4-O/P
A critical role of ceramide-CD300f interaction in septic peritonitis
Kumi Izawa (Juntendo University)
2-E-W19-16-P
Basophil-selective tryptase mMCP-11 plays crucial roles in the development of IgE-mediated chronic allergic inflammation in the skin.
Misako Iki (Tokyo Medical and Dental University)


Category-11: Allergy

3-D-W28-5-O/P
The role of Tfh cells and DCs in particulate-induced iBALT formation in the lungs
Etsushi Kuroda (Osaka University, Health and Nutrition)
3-D-W29-6-O/P
Clec10a suppresses Der f-induced immune response and dermatitis
Kazumasa Kanemaru (University of Tsukuba)


Category-12: Cytokines and chemokines

2-G-W21-1-O/P
Regulation of IL-4 production in Group2 innate lymphoid cells
Yasutaka Motomura (RIKEN-IMS)
2-G-W21-5-O/P
HBV-induced exosomal miRNAs down-regulate the expression of IL-21 mRNA by binding to its 3’UTR
Yutaka Enomoto (The University of Tokyo)


Category-13: Immunological memory

3-F-W33-2-O/P
Specific niches for lung-resident memory CD8+ T cells at the site of tissue regeneration enable CD69-independent maintenance
3-F-W33-4-O/P
Molecular mechanisms for prevention of IgE-memory formation by membrane IgE
Kei Haniuda (Tokyo University of Science)


Category-14: Virus infection

1-E-W9-3-O/P
Visualizing immune responses to influenza virus in mouse lung by using two-photon microscopy
Hiroshi Ueki (The University of Tokyo)
1-E-W10-1-O/P
Modulation of the antiviral adaptor IPS-1-mediated innate immune responses by carboxylation
Tomohiko Okazaki (The University of Tokyo)


Category-15: Mycofungal/ parasite infection

3-C-W26-7-O/P
Effect of Secreted Immunoglobulin Deficiency in Anti-Leishmania Immunity
Piyarat Srinontong (Gifu University)
3-C-W26-19-O/P
Strategy of Zygomycete fungi to evade anti-fungal innate immunity
Masashi Kanayama (Duke University)


Category-16: Bacterial infection

3-C-W27-5-O/P
Microbially cleaved immunoglobulins are sensed by the innate immune receptor LILRA2
Kouyuki Hirayasu (Osaka University)
3-C-W27-6-O/P
Recognition of mycobacterial lipid by Dendritic cell immunoactivating receptor
Kenji Toyonaga (Kagoshima University)


Category-17: Endogeneous innate immunity and inflammation

3-B-W24-17-O/P
Involvement of RNAi accessory factors in MDA5/LGP2-mediated cellular responses by Cardiovirus infection
Akihiko Komuro (Niigata University)
3-B-W24-20-O/P
Immune regulation through TRIM-regulated precision autophagy and secretion.
Tomonori Kimura (Osaka University)


Category-18: Mucosal-Skin Immunity

1-A-W1-15-O/P
Commensal bacteria-derived metabolite induce colonic IgA producing cells
Junya Isobe (Keio University)
1-A-W2-8-O/P
Immunization with GM-CSF-induced RALDH2-expressing dendritic cells induce antigen-specific IgA and Th responses in intestine


Category-19: Tolerance and Immune suppression

2-D-W18-6-O/P
Non-overlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
Baihao Zhang (Kyoto University, RIKEN-IMS)
2-D-W18-12-O/P
Hepatic IL-10 producing CD11b+ macrophage recruited in colitic mice prevent T-cell-dependent hepatitis via gut-liver axis
Nobuhito Taniki (Keio University)


Category-20: Organ-specific autoimmune diseases

3-F-W32-2-O/P
The anti-apoptotic effect of matrix metalloproteinase-2 suppresses streptozotocin-induced diabetes by activating the Akt signaling pathway
Kota Nishihama (Mie University)
3-F-W32-4-O/P
Regulation of neuroinflammation by a cellular metabolite in experimental autoimmune encephalomyelitis
Daisuke Kamimura (Hokkaido University)


Category-21: Inflammatory arthritis

2-C-W17-2-O/P
Dual Effect of 3-Bromopyruvate on Both Th17 and Treg Cell Differentiation and Dendritic Cell Activation Ameliorates Autoimmune Arthritis in Mice
Takaichi Okano (Kobe University)
2-C-W17-6-O/P
Histone lysine methylation and STAT3 differentially regulate constitutive nad IL-6-induced MMPs gene activation in rheumatoid arthritis synovial fibroblasts
Yasuto Araki (Saitama Medical University)


Category-22: Systemic autoimmune diseases

1-F-W11-5-O/P
IL-21 enhances the development of autoimmune myositis via the production of GM-CSF from gd T cells
Takahiro Kageyama (Chiba University)
1-F-W12-1-O/P
Cell-type-specific transcriptome analysis of peripheral blood mononuclear cells (PBMCs) revealed B cell contribution to systemic lupus erythematosus pathogenesis
Yusuke Takeshima (The University of Tokyo)


Category-23: Tumor immunity

2-A-W15-12-O/P
IL-33 promotes obesity-associated liver cancer development
Fumitaka Kamachi (Tokyo University of Science)
3-A-W22-5-O/P
A novel pathogenic role of interleukin-34 in cancer chemoresistance
Muhammad Baghdadi (Hokkaido University)


Category-24: Human Immunology (Immunointervention)

1-D-W7-11-O/P
Gene Modules Correlated with Disease Activity and Abatacept Treatment Identified with Weighted Gene Co-Expression Network Analysis of CD4+ T Cell Subsets of Rheumatoid Arthritis
Shuji Sumitomo (The University of Tokyo)
1-D-W8-2-O/P
Development of molecular targeted therapy for human acute GVHD in humanized mice
Genki Okumura (University of Tsukuba)


Category-25: Antigen presentation, Trafficking

3-E-W31-6-O/P
HLA-F and MHC open conformer cooperate in antigen presentation during the inflammatory response
Akiko Ishitani (Nara Medical University)
3-E-W31-8-O/P
Implications of Spns2-deficiency on S1P-driven lymphocytes egress, HEV-integrity and immunity.
Szandor Simmons (Osaka University)