ベストプレゼンテーション賞(2017年)

2017年

Category-1: Hematopoiesis and Immune Environment

1-G-W13-9-O/P
Crucial role of CD74 in hematopoietic cell differentiation
Tatsuya Shishido (Osaka University)
1-G-W13-10-O/P
Balancing population sizes of myeloid and lymphoid cells by osteopontin isoforms
Masashi Kanayama (Duke University School of Medicine)


Category-2: B cells

3-E-W34-2-O/P
FcγRIIb plays an important role in maintaining clonal ignorance and prevents pemphigus phenotype in pathogenic anti-desmoglein 3 antibody knock-in mice
Hisashi Nomura (Keio University School of Medicine)
3-E-W35-3-O/P
Germinal center B cell development by glycolysis and mitochondrial metabolism
Kei Haniuda (Tokyo University of Science)


Category-3: T cells

3-I-W42-4-O/P
Control of proinflammatory γδT cell development by linage-specific TCR signaling pathway
Ryunosuke Muro (The University of Tokyo)
3-I-W43-15-O/P
Systemic metabolic shift induced by PD-1 deficiency perturbs brain monoamines and emotional behaviour
Michio Miyajima (RIKEN Yokohama Institute)


Category-4: Helper T cells

1-I-W18-8-O/P
The transcriptional repressor Bach2 regulates differentiation of pathogenic Th2 cells
Makoto Kuwahara (Ehime University)
1-I-W18-10-O/P
IL-10-Producing Tr2 cells Induced by mTOR/CEBPβ Signaling Regulate Hyphal C. albicans Kidney Infection
Masaki Tajima (NIAID, NIH)


Category-5: Innate lymphocytes

3-B-W28-11-O/P
Role of mucosal-associated invariant T cells in lupus pathogenesis
Goh Murayama (Juntendo University School of Medicine)
3-B-W29-9-O/P
Innate and adaptive immune cells regulate Paneth cell granule formation and α-defensin secretion
Mariko Kamioka (The University of Tokyo)


Category-6: Dendritic cells and macrophages

3-C-W30-11-O/P
Early FcRγ-Erk signaling determines cytokine profile of dendritic cells through C-type lectin receptors
Miyuki Watanabe (Osaka University)
3-C-W31-7-O/P
The novel ubiquitin ligase complex, NQO1-PDLIM2 inhibits TLR-dependent production of selective cytokines by degrading IκB-ζ
Akihiro Kimura (Research Institute National Center for Global Health and Medicine)


Category-7: Mast cells & granulocytes

3-H-W40-21-O/P
STAP-2 is an adopter molecule to positively regulate basophil activation
Jun-ichi Kashiwakura (Hokkaido University)
3-H-W40-27-O/P
Basophils exert antigen presentation via trogocytosis-mediated acquisition of peptide-MHC class II complexes from dendritic cells (DCs)
Kensuke Miyake (Tokyo Medical and Dental University (TMDU))


Category-8: Allergy

1-A-W1-4-O/P
Myosin light chains 9 and 12 are functional ligands for CD69 that regulate airway inflammation
Koji Hayashizaki (Chiba University)
2-G-W23-1-O/P
The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction
Kazuhiko Yamamura (Kyushu University)


Category-9: Cytokines and chemokines

1-H-W15-9-O/P
RNA Splicing Mediator 1 (RSM1) regulates inflammation via alternative splicing of DNA methyltransferase Dnmt3b
Hironao Suzuki (Hokkaido University)
1-H-W16-4-O/P
Function of BMP2 and BMP7 produced by ILC2 in the adipose tissue
Yurina Miyajima (RIKEN IMS)


Category-10: Tolerance and Immune suppression

3-A-W26-2-O/P
Single-cell analysis of autoreactive T cells under the control of PD-1
Hikari Okamura (Tokushima University)
3-A-W26-10-O/P
Antigen-specific immune regulation mediated by TCR-like antibodies
Kazuki Kishida (Osaka University)


Category-11: Virus infection

1-D-W7-8-O/P
Induction of cell death by imiquimod (R837) and its role in immune responses
Haruna Okude (Nara Institute of Science and Technology)
1-D-W8-7-O/P
Identification of a novel HIV-1 restriction factor which selectively degrades viral transcripts.
Daichi Yamasoba (Kyoto University)


Category-12: Bacterial / mycofungal / parasite infection

1-E-W10-12-O/P
Dendritic cell-based vaccination induces lung resident memory Th17 cells that ameliorate pulmonary infection with highly virulent Cryptococcus gattii
Keigo Ueno (National Institute of Infectious Diseases)
1-E-W9-2-O/P
Glycolipids in group A Streptococcus are recognized by Mincle to trigger host immune responses
Imai Takashi (Kyushu University)


Category-13: Endogenous innate immunity and inflammation

1-B-W3-8-O/P
Intracellular metabolite, β-glucosylceramide, is an endogenous adjuvant acting through Mincle
Masahiro Nagata (Osaka University)
1-B-W4-8-O/P
Mechanisms for the regulation of adipose tissue expansion and remodeling by group 2 innate lymphoid cells
Kafi N. Ealey (RIKEN IMS)


Category-14: Mucosal-Skin Immunity

2-A-W19-3-O/P
Microbial fermentation product butyrate Ameliorates Autoimmune Arthritis.
Daisuke Takahashi (Keio University Faculty of Pharmacy)
2-A-W19-8-O/P
17,18-EpETE, a metabolite of omega-3 essential fatty acids, inhibited neutrophil mobility and ameliorated skin inflammation in DNFB-induced contact hypersensitivity model
Takahiro Nagatake (National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN))


Category-15: Tissue-specific immune diseases

3-H-W41-13-O/P
Mesenchymal-myeloid cell interactions in renal microenvironment for pathological fibrogenic machinery in kidney fibrosis
Yosuke Kurashima (The University of Tokyo)
1-C-W5-1-O/P
Eomes-positive cytotoxic T helper cells: a new pathogenic immune cell subset in secondary progressive multiple sclerosis?
Ben Raveney (NCNP)


Category-16: Systemic autoimmune diseases

3-G-W38-1-O/P
IFN-γ-T-bet mediated metabolic reprograming in T helper 1 cellsand its relevance to pathogenesis of SLE
Shigeru Iwata (University of Occupational & Environmental Health)
3-G-W38-3-O/P
Comprehensive analysis of genome and transcriptome analysis of immune cell subsets in peripheral blood mononuclear cells (PBMCs) revealed mitochondria contribution in B cells to systemic lupus erythematosus.
Yusuke Takeshima (The University of Tokyo)


Category-17: Tumor immunity

3-D-W32-11-O/P
Basic leucine zipper transcription factor ATF-like 2 exhibits an anti-tumor effect through upregulation of IL-12 p40 expression
Hisashi Kanemaru (Osaka University)
3-D-W33-1-O/P
The role of soluble CD155 in tumor immune response and metastasis
Okumura Genki (University of Tsukuba)


Category-18: Cancer immunotherapy

1-F-W11-11-O/P
Low-dose HMGN1 synergistically enhances anti-tumor immunity in CD4 depleting antibody-treated mice
Chang-Yu Chen (The University of Tokyo)
1-F-W12-10-O/P
Dying but not dead cancer cells exert the effect of cell-based cancer vaccine
Yoshino Tanaka (Hokkaido University)


Category-19: Human Immunology (Immunointervention)

1-I-W17-1-O/P
Identification of the disease causal variants in human primary biliary cholangitis (PBC) susceptibility gene loci NFKB1/MANBA
Yuki Hitomi (The University of Tokyo)