ベストプレゼンテーション賞(2015年)

2015年

Category-1: Hematopoiesis and Immune Environment

2-I-W32-7-O/P
Bach2 represses myeloid programs to promote lymphoid progenitor development under both the steady state and infection Ari Itoh-Nakadai (Tohoku University)
2-I-W32-10-O/P
Identification of cMoP and bona fide GMP in human umbilical cord blood
Shunsuke Kawamura (Tokyo Medical and Dental University)


Category-2: B cells

3-F-W42-2-O/P
Intrathymic licensing of immigrating peripheral B cells for T cell tolerance induction
Tomoyoshi Yamano (Ludwig-Maximilians-Universitat)
3-F-W42-3-O/P
Antigen-spe cific maturation of anti-nuclear antibodies in systemic lupus erythematosus
Shuhei Sakakibara (Osaka University)


Category-3: T cells

2-H-W30-1-O/P
A tumor suppressor Menin controls CD8 T cell senescence by regulating energy metabolism
Junpei Suzuki (Ehime University)
3-H-W46-3-O/P
Statistical analysis shows non-randomness of V/J gene selection in human TCR
Yotaro Katayama (The University of Tokyo)


Category-4: Helper T cells

1-H-W13-4-O/P
Obesity drives Th17 cell differentiation by inducing the lipid metabolic kinase, ACC1
Yusuke Endo (Chiba University)
1-H-W14-11-O/P
Human CXCL13-producing CD4 T cells preferentially differentiate under IL-2-limitted environment
Hiroyuki Yoshitomi (Kyoto University)


Category-5: Regulatory T cells

3-G-W43-2-O/P
Establishment of regulatory T cell-specific super-enhancers
Yohko Kitagawa (Osaka University)
3-G-W43-6-O/P
Foxp3 changes its partners and genomic binding regions in regulatory T cells in response to IL-4 stimulation
Norihito Hayatsu (RIKEN-IMS)


Category-6: Innate lymphocytes

1-C-W4-7-O/P
Involvement of Natural Helper cells, a member of group 2 ILCs (ILC2) in the induction of obesity
Takaharu Sasaki (RIKEN-IMS)
1-C-W4-2-O/P
Identification of progenitor cells specific to ILC1s and ILC3s in adult intestine
Takashi Ebihara (Washington University)


Category-7: Dendritic cells and macrophages

2-C-W20-1-O/P
Transcription factor IRF8 governs the enhancer landscape dynamics in mononuclear phagocyte development
Daisuke Kurotaki (Yokohama City University)
3-C-W36-2-O/P
Unique role of Cbfb2 variant in Langerhans cell development
Mari Tenno (RIKEN-IMS)


Category-8: Antigen presentation

1-D-W5-2-O/P
p62/Sqstm1 plays a specific role for CD8+ T cell activation in antigen presenting cells following IFN-γ-induced disruption of the Toxoplasma gondii parasitophorous vacuoles
Youngae Lee (Osaka University)
1-D-W5-13-O/P
Discovery of lipopeptide Ag-presenting molecules: its molecular identity and X-ray crystallographic structure
Daisuke Morita (Kyoto University)


Category-9: Trafficking

2-I-W31-5-O/P
Spinster-homologue-2 (Spns2) controls S1P-driven lymphocyte egress from lymphoid organs
Szandor Simmons (Osaka University)


Category-10: Mast cells & granulocytes

1-C-W3-3-O/P
The hIstidine transporter SLC15A4 regulates allergic responses by tuning the endo/lysosomal condition of mast cells
Toshihiko Kobayashi (National Center for Global Health & Medicine)
1-C-W3-4-O/P
The novel role of LMIR7/CLM-3 in mast cell- and IgE-dependent anaphylaxis
Masamichi Isobe (Juntendo University)


Category-11: Allergy

3-I-W47-4-O/P
Murine allergic rhinitis and nasal Th2 activation are mediated via TSLP- and IL-33-signaling pathways
Shoko Akasaki (Hyogo College of Medicine)
3-I-W48-4-O/P
CXCL4 is a novel nickel binding protein and augments nickel allergy at elicitation phase
Toshinobu Kuroishi (Tohoku University)


Category-12: Cytokines and chemokines

1-I-W15-4-O/P
Inflammation amplifier regulatory molecule NSZ1 controls NFκB specific chromatin accessibility via alternative splicing of a DNA methyltransferase
Toru Atsumi (Hokkaido University)
1-I-W16-8-O/P
Involvement of a novel alpha9 integrin ligand, XCL1/Lymphotactin in autoimmune diseases
Naoki Matsumoto (Hokkaido University)


Category-13: Immunological memory

1-G-W11-3-O/P
Distinct germinal center selection at local sites shapes memory B cell response to viral escape
Yu Adachi (National Institute of Infectious Diseases)
1-G-W11-5-O/P
A role of IL-9 receptor on B cells in the T-dependent immune responses
Shogo Takatsuka (Tokyo University of Science)


Category-14: Virus infection

1-F-W9-2-O/P
The role of mTOR in TLR3 responses to Herpes Simplex Virus infection
Ryota Sato (The University of Tokyo)
1-F-W10-6-O/P
CD150 costimulation enhances SHIV-specific TFH cell responses in non-human primate models
Takuya Yamamoto (National Institutes of Biomedical Innovation, Health and Nutrition)


Category-15: Mycofungal/ parasite infection

1-E-W7-14-O/P
Batf2 regulates Th17 responses by suppression of IL-23 production during Trypanosoma cruzi infection
Shoko Kitada (Osaka University)
1-E-W7-18-O/P
Malaria-induced bone disorder triggered by chronic inflammation in the bone
Michelle Sue Jann Lee (Osaka University)


Category-16: Bacterial infection

3-G-W44-6-O/P
Analysis of a novel subset of IFN-γ-producing DN2a γδ T cells in the periphery of mice
Shinya Hatano (Kyushu University)
3-G-W44-4-O/P
CD300a on mast cells and dendritic cells control the pathogenesis of experimental sepsis
Gamage Sanath Udayanga Kankanam (University of Tsukuba)


Category-17: Endogeneous innate immunity and inflammation

1-G-W12-1-O/P
MD-1 negatively regulates B cell-related inflammation
Natsuko Tanimura (The University of Tokyo)
2-G-W27-3-O/P
A Novel Function of Human Pumilio Proteins in Cytoplasmic Sensing of Viral Infection
Ryo Narita (Kyoto University)


Category-18: Mucosal-Skin Immunity

3-E-W40-1-O/P
The role of the gut microbiota in the development of experimental autoimmune encephalomyelitis
Eiji Miyauchi (RIKEN-IMS)
1-E-W8-1-O/P
Lypd8 maintains gut homeostasis through separation of flagellated bacteria and colonic epithelia
Ryu Okumura (Osaka University)


Category-19: Tolerance and Immune suppression

2-C-W19-3-O/P
Establishment of thymus transplant model to analyze peripheral T cell tolerance against pemphigus autoantigen, desmoglein 3
Hisato Iriki (Keio University)
2-C-W19-4-O/P
The strength of inhibition by LAG-3 depends on properties of APCs
Takumi Maruhashi (Tokushima University)


Category-20: Organ-specific autoimmune diseases

2-F-W25-1-O/P
RANKL on T cells is essential for inflammation in the CNS during EAE
Matteo Maurizio Guerrini (The University of Tokyo)
2-F-W26-6-O/P
Activated increased number of T follicular helper subset 2 correlates with increased levels of IgG4, IL-4 and plasmablasts in IgG4-related disease
Mitsuhiro Akiyama (Keio University )


Category-21: Inflammatory arthritis

2-B-W17-1-O/P
Rheumatoid arthritis patients-derived gut microbiota induce Th17-mediated arthritis in SKG mice
Yuichi Maeda (Osaka University)
2-B-W17-2-O/P
TIARP regulates CXCL2/CXCR2 mediated neutrophil migration via the inhibition of IL-6
Asuka Inoue (University of Tsukuba)


Category-22: Systemic autoimmune diseases

1-B-W1-5-O/P
Regulatory roles of TGF-β3 in lupus pathogenesis
Toshihiko Komai (The University of Tokyo)
1-B-W2-1-O/P
Myeloperoxidase/HLA class II complexes are targets for autoantibodies in ANCA-associated vasculitis
Ryosuke Hiwa (Kyoto University)


Category-23: Tumor immunity

2-D-W21-8-O/P
Metformin administration stimulates glycolysis of effector memory CD8TIL in tumor microenvironment Shingo Eikawa (Okayama University)
3-D-W38-5-O/P
Tumor cell death accelerated migration of tumor infiltrating dendritic cells into draining lymph nodes
Taiki Moriya (Osaka Ohtani University)


Category-24: Human Immunology (Immunointervention)

2-B-W18-3-O/P
The ulcerative colitis-associated gene RNF186 regulates gut homeostasis
Kosuke Fujimoto (Osaka University)
3-B-W34-5-O/P
Development of a human hemato-lymphoid system in human cytokine knock-in Rag2-/-Il2rg-/- mice engrafted with peripheral blood mobilized CD34+ cells
Yasuyuki Saito (Kobe University / University Hospital Zurich)