Kim is a professor in the Department of Pharmacology, Yonsei University college of Medicine, Seoul, South Korea. He received his M.D. in 2001 and Ph.D. in 2006 from Yonsei University, Seoul. During his Ph.D. programme, he studied tissue engineering using mesenchymal stem cells and biomaterials. After postdoctoral training at Emory University, Atlanta, Georgia, USA, in the field of stem cell biology, he became an independent researcher in 2010, when he changed his research field to genome editing. His laboratory is interested in genome engineering in several types of cultured cells (including stem cells) and in mammals, as well as in the development of CRISPR-Cas-based high-throughput methods for genetic studies.
　　His group developed a high-throughput method for profiling Cpf1 activity in human cells. Furthermore, his group also developed deep learning-based computational models predicting Cpf1 activity at endogenous sites with unprecedentedly high accuracy. Recently, his group generated computational models that predict the efficiencies of various Cas9 variants in a highly comparative manner and expanded the high-throughput evaluation and computational modeling to base editors and prime editor 2. His group has also generated a CRISPR clock that enable recording elapsed time into integrated DNA sequences of live mammalian cells. Ongoing projects in his lab include the development of potential therapeutic applications of CRISPR-Cas9 to various genetic diseases. His group will continue the research to improve or develop genome editing tools for biomedical research and biotechnology and apply these advanced genome editing methods as therapeutic modalities for various diseases.