JSICR/MMCB 2023 Joint Symposium



Opening Remarks
Symposium 1 Disease-associated Macrophages
ChairHiromitsu Hara (Kagoshima Univ.)
Makoto Tsuda (Kyushu Univ.)
S1-1TREM2 in Neurodegeneration and Cancer
 Marco Colonna (Washington Univ. USA)
S1-2Unraveling the Heterogeneity of Antigen-Presenting Cells in Inflammatory Skin Diseases Using Single-Cell RNA Sequencing
 Satoshi Nakamizo (Kyoto Univ.)
S1-3Identification of a novel subset of macrophages that regulate muscle regeneration
 Yumiko Ohishi (Nippon Med. Sch.)
S1-4A new mechanism for pain chronicity revealed by a microglial subset
 Makoto Tsuda (Kyushu Univ.)
S1-5The power of ONE: Immunology in the age of single cell genomics
 Ido Amit (Weizmann Institute of Science, Israel)
General Assembly & JSICR Award Lecture
MMCB General Assembly
JSICR General Assembly
JSICR Award Lecture
Symposium 2 Monogenic Disorders as Immune Rosetta Stone
Chair Kensuke Miyake(The Univ. of Tokyo)
Tsuneyasu Kaisho(Wakayama Med. Univ.)
S2-1 Human inborn errors of immunity model mice for autoinflammation,autoimmunity and/or immunodeficiency
Tsuneyasu Kaisho(Wakayama Med. Univ.)
S2-2 Immunodeficiency and autoinflammation caused by dysfunction of immunoproteasomes
Koji Yasutomo(Tokushima Univ.)
S2-3 Autoinflammatory disease due to G-CSF
Seth Masters (WEHI, Australia)
S2-4 The molecular mechanism underlying STING degradation at lysosomes
Tomohiko Taguchi(Tohoku Univ.)
S2-5 Lysosomal nucleic acid stress diseases
Kensuke Miyake(The Univ. of Tokyo)
Workshop 1 Innate Immune Cells in Health and Disease
Chair Osamu Takeuchi (Kyoto Univ.)
Taro Kawai (NAIST)
WS1-1 Endosomal abnormalities in dendritic cells cause autoimmune hepatitis and primary biliary cholangitis
Shin-Ichiroh Saitoh (The Univ. of Tokyo)
WS1-2 Semaphorin 7A promotes neutrophil activation and neutrophil extracellular trap formation
Shoji Kawada (Osaka Univ.)
WS1-3 A stress sensor IRE1α is involved in bacterial exotoxin-induced inflammasome activation in tissue-resident macrophages
Izumi Sasaki (Wakayama Med. Univ.)
WS1-4 The Regnase-1/3-Nfkbiz axis controls hematopoietic lineage priming
Takuya Uehata (Kyoto Univ.)
WS1-5 Myeloid-like B cells protect the host by boosting myelopoiesis during infection
Masashi Kanayama (TMDU)
WS1-6 Microglia activation by β-GlcCer causes phagocytosis of neurons that exacerbates Gaucher disease
Takashi Shimizu (Osaka Univ.)
WS1-7 Antigen cross-presentation by Alveolar macrophages during viral infection
Takumi Kawasaki (Nagasaki Univ.)
Workshop 2 Advances in Cytokine Research for Disease Pathophysiology
Chair Akinori Takaoka (Hokkaido Univ.)
Hiroki Yoshida (Saga Univ.)
WS2-1 Suppression of itch sensation by IL-27
Daiji Sakata (Kagoshima Univ.)
WS2-2 CD8+ T-cell memory induced by SARS-CoV-2 mRNA vaccination is maintained by clonal replenishment
Satoshi Ueha (Tokyo Univ. of Sci.)
WS2-3 The role of inflammatory cytokines in B-ALL development
Aisa Suzuki (Tokyo Univ. of Sci.)
WS2-4 Nucleolus dysfunction-induced DNA leaking alters innate immune response under nutrition starvation
Ken Takashima (Kumamoto Univ.)
WS2-5 Impaired plasma cell generation in a model mouse of the proteasome-associated autoinflammatory syndromes with immunodeficiency
Takashi Kato (Wakayama Med. Univ.)
WS2-6 Comprehensive mapping of extracellular particles during viral infection by high esolution flow cytometry
Tomoya Hayashi (IMSUT / VDesc / NIBIOHN)
Poster Viewing

May 26

Symposium 3 The Forefront of Covid-19 Research
ChairYumiko Imai (NIBIOHN)
Hiroyuki Oshiumi (Kumamoto Univ.)
S3-1ACE2- at the heart of a pandemic
 Josef Penninger (Univ. British Columbia, Canada)
S3-2Therapeutic effects of angiotensin converting enzyme 2 (ACE2) enzyme activity on severe acute lung injury in COVID-19
 Keiji Kuba (Kyushu Univ.)
S3-3Mechanisms of severe disease and sequelae and potential for drug discovery – Medical big data and basic analysis
 Yumiko Imai (NIBIOHN)
S3-4Unusual type I interferons are associated with cholesterol metabolism and prime the antiviral innate immune response
 Hiroyuki Oshiumi (Kumamoto Univ.)
Luncheon Seminar (Co-sponsored by Sanofi)
Chair Yoshiki Tokura (Chutoen General Medical Center)
LS-1 The role of group 2 innate lymphoid cells in ulcerative colitis
Kazuyo Moro (Osaka Univ.)
LS-2 Regulation of type 2 inflammation as a therapeutic approach for atopic dermatitis
Tetsuya Honda (Hamamatsu Univ. Sch. Med.)
Afternoon Seminar (Co-sponsored by Bristol-Myers Squibb K.K.)
Chair Atsushi Otsuka (Kinki Univ.)
AS-1 New treatment strategy for psoriasis ~Deucravacitinib, an oral selective TYK2 inhibitor~
Masahiro Kamata (Teikyo Univ.)
Chair Nobuo Kanazawa (Hyogo Med. Univ.)
AS-2 Roles of the IL-23-IL-17A/F axis in the development of psoriasis
Yoichiro Iwakura (Tokyo Univ. of Sci.)
Symposium 4 Imaging of Immune Cells Interaction
ChairKenji Kabashima (Kyoto Univ.)
Takaharu Okada (RIKEN IMS)
S4-1Probing Tissue Macrophage functions in Health and Disease
 Steffen Jung (Weizmann Institute of Science, Israel)
S4-2Newly identification of a CXCR6+ pathogenic skin-resident CD4+ T cell subset in a mouse model of allergic dermatitis that requires CXCL16 for its maintenance
 Kenji Kabashima (Kyoto Univ.)
S4-3Spatiotemporal development of dendritic cell networks
 Wolfgang Kastenmüller (Universitat Wurzburg, Germany)
S4-4The role for sensory neuronal IL-31 receptor and STAT3 in inflammatory itch
 Takaharu Okada (RIKEN IMS)
Poster Award Ceremony
Closing Remarks